The United States Pharmacopeia (USP) has adopted a pre-compendial approach to enhance engagement with stakeholders and to develop standards that are fit for purpose. As part of this approach, the qNMR community in China (qNMR-C) was established in March 2022. This community attracted over 20 subject matter experts who actively participate in its regular activities. The objective of the qNMR community is to foster a collaborative environment where practitioners can share ideas, exchange knowledge, introduce new techniques, build capabilities, and discuss best practices. This collaborative effort aims to bolster the adoption and practical application of qNMR. The USP spearheads numerous qNMR-C events, as outlined in Table 1. Through this presentation, we intend to provide updates on qNMR advancements and encourage ongoing learning and knowledge sharing among those interested in qNMR. Additionally, we aim to underscore the significance of qNMR and its applications to a broader audience. Our initiative includes creating resources to engage students, researchers, and industry professionals who might be unfamiliar with qNMR. These dedicated efforts assist USP and its stakeholders in gaining a deeper understanding of qNMR technique and exploring its potential opportunities in compendial contexts.
Table 1. qNMR events organized for qNMR-C from 2021 to 2024
| Column 1 | Column 2 | Column 3 | Column 4 |
|---|---|---|---|
| Event | Date | Agenda | |
| Presentation | Speaker | ||
| USP qNMR Symposium | December 16th -17th, 2021 | USP Quantitative NMR Symposium | |
| qNMR-C kick-off meeting | March 11th, 2022 | https://www.linkedin.com/pulse/qnmr-scientific-community-china-qnmr-c | |
| Webinar | April 28th, 2022 | NMR Instrument Qualification | Huiwen Deng, Bruker BioSpin |
| Webinar | June 17th, 2022 | Good Weighing Practice - For Accurate qNMR Sample Preparation | Klaus Fritsch, Mettler Toledo |
| Webinar | July 26th, 2022 | Proposed revisions to the USP NMR General Chapter <761> | Toru Miura, FUJIFILM Wako Pure Chemical Corporation |
| Webinar | September 26th, 2022 | Proposed revisions to the USP NMR General Chapter <1761> | Joe Ray, University of Illinois, at Chicago; Christina Szabo, Baxter International Inc. |
| Webinar | November 10th, 2022 | Use of qNMR to determine HPLC relative response factors for botanical reference standards used in pharmacopeial monographs | Caiying Ma, US Pharmacopeia |
| USP 2nd qNMR Symposium | January 9th - 11th, 2023 | https://web.cvent.com/event/summary | |
| Webinar | March 29th and April 27th, 2023 | qNNR concepts, principles and method development and validation | Yang Liu, US Pharmacopeia |
| Webinar | September 8th, 2023 | qNMR Education and training in Tianjin University | Xiaojuan Deng, Tianjin University |
| Webinar | October 12th, 2023 | qNMR and uncertainty | Wei Zhang, Natioal Institute Metrology, China; Yang Liu, US Pharmacopeia |
| USP 3rd qNMR Symposium | December11th, 2023a | https://www.usp-edu.org/uploads/1/image/public/202311/2023-12-11.pdf | |
| Webinar | March-20th, 2024 | Quantitative applications of benchtop NMR | Jingwen Du, Qingdao Tenglongweibo Technology Co., Ltd. |
| Webinar | to be updated | Quantitative applications of solid-state NMR | Yongchao Su, Merck & Co., Inc. |
